Question 1

Is this magnesium orotate?

Accepted Answer

This is not magnesium orotate (orotic acid), it is magnesium lysinate glycinate chelate. Which to my understanding means a magnesium chelate complex with one lysine and one glycine molecule bonded to one magnesium atom. The product is sourced by Albion Laboratories, Inc. I would not recommend the orotate form of magnesium, because it's actually magnesium bis-orotate. This is due to the fact that magnesium has a ionic charge of +2 and orotatic acid has a ionic charge of -1, so magnesium ends up bonding to two orotate molecules. This is not good because it's believed the two orotate molecules prevent it, structurally, from being able to dock within the uridine monophosphate synthetase ("UMPS") enzyme. Should it be able to dock, it may (I'm speculating) interfere with orotidine-5'-phosphate decarboxylase (ODCase), as this is believed to be the case with lithium orotate. I'm of the opinion that only cations with a charge of +1 are useful in orotate form, i.g. lithium, sodium, and potassium.This form of magnesium, along with magnesium glycinate and magnesium bis-glycinate are the best forms of magnesium to use if you're supplementing for mental health reasons. Glycine is a neurotransmitter and NMDA co-agonist. NMDA dysfunction has been implicated in many mental health disorders, especially in particular psychotic symptoms and schizophrenia. Thus magnesium glycinate has a dual acting effect on NMDA receptors, helping to restore normal NMDA function.

Question 2

The coating disappears rapidly as soon as I put it in my mouth.  I've choked on it a few times.  Any suggestions for getting this down easier?

Accepted Answer

Don't drink cold water with these pills,they will freeze your throat and make it harder to swollow,drink room temp water,no milk or juice it dilutes the magnesium so your not getting the full amount. You swallow food bigger than this pill,so you can swallow it. I had thyroid removed and have a hard time with big pills,but they help me so much with muscles pain I can't live without them. I have tried different brands, this one works the best. I'm on my 5th order!

Question 3

How long is each tablet?

Accepted Answer

These tablets are big, but can easily be chewed or crushed and mixed into Applesauce, Peanut butter, Nutella, Yogurt or whatever suits your taste buds.

Question 4

How does this type Magnesium compare with the Taurate form? "information overload" online! Just want the best most readily absorbed beneficial! :)

Accepted Answer

The cheapest form of Magnesium usually contains magnesium oxide, which may not be absorbed as well and may cause diarrhea in some people.  Doctor's Best contains magnesium glycinate and magnesium lysinate chelate.  Chelate is supposed to improve absorption.  Taurate is an amino acid which some feel helps with migraines and may help to improve cardiac function (there is no formal study proving that taurate helps, it is just a belief).

Doctor’s Best High Absorption Magnesium Glycinate Lysinate Supplement - 100% Chelated for Maximum Absorption - Magnesium for Sleep and Muscle Relaxation - 200 Mg Per Serving - 240 Tablets

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